Edward Wilson is the Pellegrino University Research Professor, Emeritus, at Harvard. He has won two Pulitzer Prizes for his books and has gained international recognition as one of the most influential scientists of all time.

Professor Wilson discusses the gradual process of large-scale extinction, explaining that we are "trimming many species back, and, as that happens, we start taking out entire genuses or families." Scientists have only partly discovered the diversity of life, and though there are currently 1.7 million known species, the estimate range for the number of existing species is anywhere from 10 million to 100 million. Professor Wilson discusses the "radical transformation" that will soon occur due to the new information available about microscopic and ultramicroscopic organisms. "We are living on an unexplored planet," he says, "but now we have the technology to make a big leap forward in exploring this from the Eukaria to the micro-organisms."

Human actions are accelerating the ongoing destruction of the environment in which these "marvelous three and a half billion years of evolutionary products exist." These human actions can be summarized with the acronym HIPPO, signifying habitat destruction (including the effects of climate change), invasive species (which invade countries, wreaking havoc and displacing native species), pollution, over-population, and over-harvesting (which drives species to extinction by killing too many individuals). One illustration of habitat destruction is NASA's estimation that five percent of the earth's surface is burned by humans yearly, the result of which is the extinction of species such as the golden toad.

Professor Wilson discusses particular locations where species extinction is most rampant, noting national parks and the rainforest of the Philippine Islands, which was originally one of the most species-rich rainforests in the world. "Now we have to stop it and maybe reverse it, otherwise we're going to lose a very large part of the Philippine fauna," Professor Wilson says. In North America, the old-growth forests have been progressively cut back and eliminated during European colonization and they currently cover only one percent of their original area. Professor Wilson emphasizes that we can "reverse the trend, or at least bring it to a halt if we bring our best resources... and if we use science productively." In order to do this, we should focus on hot spots, which are locations containing the largest number of species. 25 discovered hot spots cover only 1.4% of the earth's surface and contain roughly 40% of the known plant and animal species. "If we can save that 1.4 percent," says Professor Wilson, "we will have taken a giant leap forward in stopping the extinction spasm."